It plays a role in how your page is seen by search engine crawlers, and how it appears in serps. Chemical product and company identification product. It is produced in large quantities for use in industry. Nitrobenzene content wt, % min 99 unnitrated hydrocarbons benzene wt, % max 0,2 1,3dinitrobenzene wt, % max 0,1 nitrophenyls wt, % max 0,01 water wt, % max 0,3 section 3. Covid19 is an emerging, rapidly evolving situation. N dangerous for the r50 environment for the full text of the rphrases mentioned in this section, see section 16. This fact sheet is a summary source of information of all. Buy 1bromo2nitrobenzene cas 577195, a biochemical for proteomics research, from santa cruz. A meta description is an html tag in the html code of your website, which allows you to customize a section of text that describes the page itself. Prepare a solution of mgl of 1chloro3nitrobenzene and dilute it to 10 ngl. It is used in the manufacture of aniline, benzidine, and other organic chemicals. Original spectra of these compounds are available on the ch 2280 website and authentic commercial samples are available in the balance room for mp and tlc comparison. Nitrobenzene is a yellowish, oily, aromatic nitrocompound with an almondlike odor that emits toxic fumes of nitrogen oxides upon combustion.
B oth batch and continuous processes employing mixed nitric and sulfuric acids are used to make nitrobenzene. The report indicates that nitrobenzene has weak carcinogenic activity in rodents after chronic inhalation exposure and may express carcinogenic. Synthesis of aniline and benzaldehyde derivatives from. Nitrobenzene was hydrogenated to aniline in the liquid phase, using raney nickel, ruthenium on carbon, rhodium on carbon, rhodium on alumina, and nickel on inert carrier catalysts. Nitrobenzene article about nitrobenzene by the free. Most of the nitrobenzene produced in the united states is used to manufacture a chemical called aniline. Nitro benzene material safety data sheet cas no 98953. Nitrobenzene is primarily used in the manufacture of aniline, but is also used in the manufacture of lubricating oils, dyes, drugs, pesticides, and synthetic rubber. Rt 111, rb 211, rl 311 molecular research center, inc. It is an oily yellow liquid with an almondlike odor. Thermal hazard assessment of nitrobenzenedinitrobenzene. Show this safety data sheet to the doctor in attendance. General procedure for the reaction of nitrobenzene with d7benzyl alcohol. Nitrobenzene levels in air have been measured in urban, rural, and waste disposal areas in new jersey.
Compare your data with those of 31hydroxyethylaniline, 31hydroxyethyl nitrobenzene, and 3aminoacetophenone. For water samples, a series of standard solutions containing each of the nitrobenzene compounds at seven concentrations, i. Most air samples taken in 1982 were negative for nitrobenzene, and the positive samples taken from residential areas were about 0. It has an odor characteristic of bitter almonds or shoe polish. For soil samples, nonpolluted soil was used as blanks for matrixmatched standard calibrations. Material safety data sheet nitrobenzene msds section 1. Please get in touch with any questions you may have. Absorption of nitrobenzene through the skin is rapid. Jan 21, 2015 nitrobenzene can be smelled in water when it is present at 0. Eastman kodak company to usepa submitting enclosed material safety data sheet and toxicity report. Source of sample, mcb manufacturing chemists, norwood, ohio. Surrogate standards are added to all samples, method blanks, matrix spikes, and calibration standards.
The information contained in this material safety data sheet is based upon available data and believed to be correct. Nitrobenzene is produced by nitration of benzene by a nitrating mixture. Hazards identification potential acute health effects. General procedure for the hd exchange reaction between aniline and d. P270 do not eat, drink or smoke when using this product.
Duration of exposure, concentration of the substance. Commercially nitrobenzene can be either produced in a batch or by a continuous process. Material safety data sheet s ection 1 1chloro3nitrobenzene 1 chemical product and company identification msds name. Material safety data sheet s ection 1 1chloro3 nitrobenzene 1 chemical product and company identification msds name. This concentrat ion may need to be adjusted depending on the detector chosen and its sensitivity. I work at, so i am a little biased, but i believe it is the best work management software. Nitrobenzene is on the hazardous substance list because it is regulated by. Nitrobenzene can be smelled in water when it is present at 0. If inhaled if breathed in, move person into fresh air.
The hazard fields include special hazard alerts air and water reactions, fire hazards, health hazards, a reactivity profile, and details about reactive groups assignments and potentially incompatible absorbents. It is poisonous, with a maximum permissible concentration in air of 3 mgm 3 in work areas and 0. Nitrobenzene article about nitrobenzene by the free dictionary. Possibly carcinogenic to humans nitrobenzene reproductive toxicity presumed human reproductive toxicant specific target organ toxicity single exposure no data available specific target organ. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. In the present work, representative samples of nitrobenzene containing 2030% dinitrobenzene and less than 1% dinitrophenol, 1% picric acid, and 1% sodium hydroxide were tested by differential scanning calorimetry dsc and accelerating rate calorimetry arc to investigate their thermal stability relative to the pure substances. Nitrobenzene is also used to mask unpleasant odors in shoe and floor polishes, leather dressings, paint solvents, and other materials. Do not eat, smoke, or drink where dinitrobenzene is. Nitrobenzene is manufactured commercially by nitration of benzene also a common air pollutant using a mixture of nitric and sulfuric acids. Cdc niosh pocket guide to chemical hazards nitrobenzene. When working with nitrobenzene, we must be very careful because it is extremely toxic. P271 use only outdoors or in a wellventilated area. Analysis of nitrobenzene compounds in water and soil. It dissolves only slightly in water and will evaporate to air.
Wear appropriate protective eyeglasses or chemical safety goggles as described by oshas eye and face protection regulations in 29 cfr 1910. The most current msds can be obtained from chevron phillips chemical company by calling 800 8525530 and should be carefully examined. Information in this sds is from available published sources and is believed to be accurate. The analysis of honey samples for residues of nitrobenzene and petroleum from the possible use of frow mixture in hives article in food chemistry 844. Mar 03, 2011 nitrobenzene is an industrial chemical. It is not known what nitrobenzene levels result in harmful health effects in people. Compare your data with those of 31hydroxyethylaniline, 31hydroxyethylnitrobenzene, and 3aminoacetophenone. Thermal hazard assessment of nitrobenzenedinitrobenzene mixtures. Sds of 1bromo4nitrobenzene, safety data sheets, cas 586787. The information provided in this safety data sheet is correct to the best of our knowledge, information and belief at the date of its publication. Material safety data sheet nitrobenzene pure section 1. Signs and symptoms of acute exposure to nitrobenzene may be severe and include cyanosis blue tint to the skin and mucous membranes, tachycardia rapid heart rate, hypotension low blood pressure, and cardiac arrhythmias.
The information given is designed only as a guidance for safe handling, use, processing, storage, transportation, disposal and release and is not to be considered a warranty or quality specification. In the laboratory, it is occasionally used as a solvent, especially for electrophilic reagents. Factors affecting extraction efficiency spme fiber selection, acidity, temperature, salt addition, extraction time, headspace, etc were verified. Nitrobenzene page 2 of 6 this fact sheet is a summary source of information of all potential and most severe health hazards that may result from exposure. Approximately 95% of nitrobenzene is consumed in the production of aniline, which is a precursor to rubber chemicals, pesticides, dyes, explosives, and pharmaceuticals.
Nitrobenzene had been clearly shown through scientifically valid testing. Nitrobenzene msds resource conservation and recovery act. Those derivatives are used to produce a wide range of. The information in cameo chemicals comes from a variety of data sources. Nitrobenzene is mainly used in the production of aniline. The analysis of honey samples for residues of nitrobenzene. Safety data sheet northwest missouri state university. Nitrobenzene is an organic compound with the chemical formula c6h5no2.
No information is available regarding cancer in humans or animals from nitrobenzene exposure. A headspace solid phase microextraction coupled with gas chromatography mass spectrometry hsspmegcms method was established for analyzing nitrobenzene, benzene and aniline in environmental water samples simultaneously. Analysis of nitrobenzene compounds in water and soil samples. Ch 2280 procedure for metalacid reduction of nitro. Nitrobenzene cas 98953 scbt santa cruz biotechnology.
Aniline material safety data sheet cas no 62533 sdsmsds. It is a waterinsoluble pale yellow oil with an almondlike odor. Identification of the substancemixture and of the companyundertaking. A two year study titled a chronic inhalation toxicity study of nitrobenzene in b6cf1 mice, fischer 344 rats and spraguedawley rats, was released by the chemical industry institute of toxicology ciit.
Although it has a pleasant almondlike smell, it will not be good to ingest. Methanol safety data sheet according to federal register vol. Nitrobenzene is an organic compound with the chemical formula c 6 h 5 no 2. No warranty, express or implied, is made and labchem inc assumes no liability resulting from the use of this sds. Dinitrobenzene mixed isomers page 3 of 6 on skin contact with dinitrobenzene, immediately wash or shower to remove the chemical. It is produced on a large scale from benzene as a precursor to aniline. It has been replaced by less toxic chemicals for this purpose.
Disclaimer the sds samples above are collected from the internet by chemblink and displayed here for the tutorial purpose only. First aid measures general advice consult a physician. Use of the information, documents and data from the echa website is subject to the terms and conditions of this legal notice, and subject to other binding limitations provided for under applicable law, the information, documents and data made available on the echa website may be reproduced, distributed andor used, totally or in part, for noncommercial purposes provided that echa is. At the end of the workshift, wash any areas of the body that may have contacted dinitrobenzene, whether or not known skin contact has occurred. Sds of 1bromo4nitrobenzene, safety data sheets, cas 586. Nitrobenzene is also used to produce lubricating oils such as those used in. In a survey of 862 hazardouswaste sites, nitrobenzene was detected in groundwater at 3 sites, at a geometric mean concentration of 1. Redistilled, as oil of mirbane, nitrobenzene had been used as an inexpensive perfume for soaps. Nitrobenzene, the simplest aromatic nitro compound, having the molecular formula c 6 h 5 no 2. Nitrobenzene is a colourless to pale yellow, oily, highly toxic liquid with the odour of bitter almonds. Examples safety data sheet sdsmsds here you can see examples of safety data sheets in some of the various languages we handle.
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